MACHEREY-NAGEL manufactures the highest quality analytical products for Filtration, Rapid Tests, Water Analysis, Chromatography and Bioanalysis.
A Company with Tradition and Future
MACHEREY-NAGEL was founded in 1911 in Düren as a specialist manufacturer of filter papers. Since that time, we have evolved into an innovative international company for chemical and biomolecular analysis. MACHEREY-NAGEL stands for innovative and creative solutions which we have a penchant for developing in-house. In addition to the “traditional” departments, such as research, production, sales and media design, we also have departments such as mechanical engineering and device development as well as our own joinery.
Our products are among the world’s most reliable analytical systems. They are used, for example, in industry, healthcare, biotechnology, environmental analysis and research. Numerous patents and international certifications underscore the high quality of our products and the competence of our employees.
Plasmid DNA
As pioneer in nucleic acid purification technologies, MN is developing plasmid purification products of highest quality for about 30 years. Today we offer a comprehensive portfolio of plasmid purification kits enabling highest purity, excellent yield, and very fast processing.
Clean-up Kits
MACHEREY‑NAGEL’s clean up kits focus on fast, easy to handle, and quantitative high recovery DNA and RNA purification. Based on different purification technologies, you can select the optimal solution for low to high throughput as well as for high quality downstream applications.
DNA Purification Kits
Combining selective purification technologies and chemistries, we offer a comprehensive range of specialized DNA isolation kits for a broad range of diversified starting materials. The resulting high quality DNA serves as excellent basis for following demanding downstream applications.
RNA Purification Kits
Our ready to use kits isolate high quality RNA including small RNA (miRNA) from various sample material with highest lysis efficiency. The handling is convenient and user‑friendly. Take advantage of our experience as RNA experts.
Viral RNA/DNA
Our viral RNA and DNA isolation kits have been optimized for use with cell‑free biological fluids and diverse veterinary and clinical samples. They are specialized for low viral titers and large sample volumes and are characterized by highest consistency and sensitivity for different types of viruses.
Protein
We provide ready to use resins or columns for GST‑tag and His‑tag purification. Our products show market leading performance. Using our protein purification products you can save mones without making compromises.
pH Tests
A large variety of different pH test paper types is provided by MN:
- pH Fix – Non bleeding pH test strips
- pH universal indicator paper – Standard in many applications
- PEHANON – pH determination in colored samples
Semi Quantitative Test Strips
Test papers and test strips for semi quantitative analysis are extremely simple to handle. They are based on the principle of “Dip&Read”. They are available for a variety of parameters and comply with all requirements of a modern rapid test. The evaluation of these tests is carried out by a comparison with a colour scale.
Qualitative test papers – Without colour chart
Qualitative test papers come without a colour scale. With little effort, the presence of ions and other substances can be detected. The test papers change their colour when the concentration is above the specified limit of detection.
Cellulose Filters
- Ashless filter papers
- Ashless hardened filter papers
- Qualitative filter papers
- Qualitative hardened filter papers
- Technical filter papers
- Chromatography papers
Glass Fiber Filters
- Glass fiber filters without binder
- Glass fiber filters with binder
- Quartz fiber filters
Membranes
Extraction Thimbles
- Cellulose extraction thimbles
- Glass fiber extraction thimbles
Special Filter Products
- Weighing aids
- Phase separation papers
- Lens paper - José paper
- Ion exchange papers
- Antibiotic resistency paper
- Surface protection paper
- Filtering aids
Syringe Filters
MACHEREY-NAGEL supply laboratories around the world with HPLC, GC and SPE columns, TLC/HPTLC plates, autosampler vials, closures and more.
MACHEREY-NAGEL and Chromatography
We provide optimal and reliable solutions for your laboratory work in sample preparation, method development and routine analysis.
MACHEREY-NAGEL Chromatography – complete solutions for your analysis
From a pioneer in chromatography to a full-range supplier of laboratory consumables, we supply laboratories around the world with HPLC, GC and SPE columns, TLC/HPTLC plates, autosampler vials, closures and more.
MACHEREY-NAGEL offers a versatile range of ready-to-use TLC and HPTLC layers, which are the result of 50 years of continuous research and development in thin layer chromatography.
The comprehensive range of TLC products from MACHEREY-NAGEL includes:
TLC/HPTLC glass plates
ADAMANT, SIL G or SIL HD are silica layers on glass backing. It’s hard to imagine a laboratory without our reliable TLC and HPTLC glass plates.
ALUGRAM and POLYGRAM TLC/HPTLC sheets are easy to handle, lightweight and flexible.
High performance silica on ALUGRAM Xtra sheets provides outstanding wettability for precise colourisation results. Moreover these TLC sheets are easy to cut with scissors.
Accessories
In addition to high quality TLC plates and sheets, we offer staining reagents and developing chambers, as well as introductory sets for educational purposes.
TLC Backings & Supports
TLC/HPTLC plates and sheets consist of an adsorbent stationary phase on a backing support.
MACHEREY-NAGEL offers three different backings:
- Glass plates
- Aluminium sheets
- Polyester sheets
Properties of TLC backings
Glass Plates
- Thickness (approx.): 1.3mm
- Weight and storage requirements: high
- Torsional strength: ideal
- Temperature stability: high
- Susceptible to breakage: yes
- Can be cut with scissors: no
- Chemical resistance against solvents: high
- Chemical resistance against mineral acids and concentrated ammonia: high
- Suitability for aqueous detection reagents: depends on phases (layer)
Glass plates are robust, heat proof and chemically resistant to all common mobile phases and visualisation reagents. They are the traditional option in TLC/HPTLC and are widely used in the pharmaceutical sector and other laboratory environments.
Aluminium Sheets - ALUGRAM Xtra
- Thickness (approx.): 0.15mm
- Weight and storage requirements: low
- Torsional strength: relatively high
- Temperature stability: high
- Susceptible to breakage: no
- Can be cut with scissors: yes
- Chemical resistance against solvents: high
- Chemical resistance against mineral acids and concentrated ammonia: low
- Suitability for aqueous detection reagents: ALUGRAM: low to moderate, ALUGRAM Xtra: moderate to high
Aluminium sheets are easy to handle, lightweight and flexible. High performance silica on ALUGRAM Xtra sheets provides outstanding wettability for precise colourisation results, even with 100% aqueous detection reagents. Moreover, ALUGRAM Xtra sheets are easy to cut with scissors. No flaking of silica occurs!
Polyester Sheets – POLYGRAM
- Thickness (approx.): 0.2mm
- Weight and storage requirements: low
- Torsional strength: low
- Temperature stability: maximum 185°C
- Susceptible to breakage: no
- Can be cut with scissors: yes
- Chemical resistance against solvents: high
- Chemical resistance against mineral acids and concentrated ammonia: high
- Suitability for aqueous detection reagents: good
Polyester sheets are easy to handle, lightweight and flexible, and can also be cut with scissors. Developed POLYGRAM sheets can also be stored for documentation in laboratory notebooks.
TLC and HPTLC
'TLC' and 'HPTLC' are both widely used terms in laboratory environments, but what is the difference? At MACHEREY-NAGEL, we define 'HPTLC' where at least one of the following criteria is being fulfilled:
- Layers with particle size 2–10 μm
- Layers prefixed with 'Nano'
- Modified layers
Narrow fractionation of HPTLC silica particles allows:
- Sharper separations
- Shorter developing times
- Shorter migration distances
- Smaller samples needed
- Increased detection sensitivity (compared to TLC)
