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VPS51 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA558869

Product Code. 15746741

  • 514.00 EUR / 100µL

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Description

Description

Immunogen sequence: FDPEVYLDKL RRECPLAQLM DSETDMVRQI RALDSDMQTL VYENYNKFIS ATDTIRKMKN DFRKMEDEMD RLATNMAVIT DFS Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

VPS51
Polyclonal
Unconjugated
VPS51
1110014N23Rik; 3110057M17Rik; AI837850; ANG2; ANG3; Another new gene 2 protein; C11orf2; C11orf3; Ffr; PP5382; Protein fat-free homolog; vacuolar protein sorting 51 homolog; vacuolar protein sorting 51 homolog (S. cerevisiae); vacuolar protein sorting-associated protein 51 homolog; VPS51; VPS51 GARP complex subunit; VPS51, GARP complex subunit
Rabbit
Antigen affinity chromatography
RUO
738
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry, Western Blot
0.3 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q9UID3
VPS51
Recombinant protein corresponding to Human VPS51
100 μL
Primary
Human
Antibody
IgG
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