missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Analysis Products
  4. Cell Based Assays
  5. Signal Transduction Reagents and Kits
  6. Thermo Scientific Chemicals U0126, ≥99%

Thermo Scientific Chemicals U0126, ≥99%

Product Code. 15423859
Click to view available options
Quantity:
25 mg
100 mg
300 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective inhibitor of mitogen-activated protein kinases MEK-1 and MEK-2

U0126, is used as a selective MAP Kinase Kinase (MKK, MEK) inhibitor. U-0126 has been observed to inhibit promoters containing an AP-1 response element, while in contrast having no effect on promoters that lack an AP-1 response group. U-0126 is also useful in neuronal studies in mice since it displays inhibitory effects against oxidative stress. U-0126 is an activator of PGC-1, mtTFA and nuclear respiratory factor.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 109511-58-2
Molecular Formula C18H16N6S2, C18H16N6S2
Synonym 1,4-Diamino-2,3-dicyano-1,4-bis(2-aminophenylthio)butadiene

Specifications

Quantity 100 mg
Description White
Content And Storage -30°C to -10°C
For Use With (Application) Selective inhibitor of mitogen-activated protein kinases MEK-1 and MEK-2
Formula Weight 380.49g/mol
Solubility Soluble in DMSO; Poorly soluble in ethanol and water
Product Type Signal Transduction Reagent
Form Powder
InChI Key DVEXZJFMOKTQEZ-JYFOCSDGSA-N
SMILES N\C(SC1=CC=CC=C1N)=C(\C#N)/C(/C#N)=C(\N)SC1=CC=CC=C1N
IUPAC Name (2Z,3Z)-bis({amino[(2-aminophenyl)sulfanyl]methylidene})butanedinitrile
Molecular Weight (g/mol) 380.49
Assay ≥99%
Show More Show Less

RUO – Research Use Only

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.