missing translation for 'onlineSavingsMsg'
Learn More

Thermo Scientific Chemicals SB 225002

A potent, selective and competitive antagonist of the G-protein coupled receptor CXCR2

Brand:  Thermo Scientific Chemicals J65387.#0

Quantity 5 mg

 View more versions of this product

Product Code. 15486869

Request Bulk or Custom Format

This item is currently unavailable or has been discontinued.
View the product page for possible alternatives.
View alternative products »

This item is not returnable. View return policy

Description

Description

SB 225002 is a selective non-peptide CXCR2 inhibitor which suppresses IL-8 induced neutrophil chemotaxis and margination. In addition, SB 225002 reduces MPO activity, IL-1β, MIP-2, and keratinocyte-derived chemokine (KC) levels. Further studies suggest that SB 225002 decreases the expression of vascular endothelial growth factor, inducible NOS (NO synthase), and Cox-2 (cyclooxygenase-2 proteins) in colon tissue.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY
Specifications

Chemical Identifiers

182498-32-4
C13H10BrN3O4
1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea

Specifications

5 mg
-30°C to -10°C
182498-32-4
352.10g/mol
Moisture Sensitive
Signal Transduction Reagent
Yellow
A potent, selective, and competitive antagonist of the G-protein coupled receptor CXCR2
C13H10BrN3O4
1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea
Soluble to 100mM in DMSO and to 50mM in ethanol
Solid
Product Suggestions

Product Suggestions

Videos
SDS Documents

Documents

Certificates

Certificates

A lot number is required to show results for certificates. To find your lot number on previous orders use our order status area.

5 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberS04L006 Certificate TypeCertificate of Analysis Date05/06/2025 Catalog NumberJ65387.#0
Lot NumberQ22L023 Certificate TypeCertificate of Analysis Date17/05/2025 Catalog NumberJ65387.#0,J65387.MA
Lot NumberQ22L023 Certificate TypeCertificate of Analysis Date23/04/2025 Catalog NumberJ65387.#0
Lot NumberQ27I030 Certificate TypeCertificate of Analysis Date17/11/2022 Catalog NumberJ65387.#0,J65387.MA
Lot NumberW07I013 Certificate TypeCertificate of Analysis Date16/09/2022 Catalog NumberJ65387.#0,J65387.MA
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title
Thermo Scientific Chemicals SB 225002 > 5mg

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.