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Thermo Scientific Chemicals Moxifloxacin hydrochloride

Moxifloxacin hydrochloride, CAS # 186826-86-8, is a broad-spectrum compound with antibacterial activity against both gram-positive and gram-negative bacteria. It also shows inhibitory activity against topoisomerase II.

Brand:  Thermo Scientific Chemicals 457960010

241.90 EUR valid until 2025-12-31
Use promo code "25339" to get your promotional price.



Quantity 1 g

Product Code. 15595986

  • 244.00 EUR / 1g

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Description

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Moxifloxacin hydrochloride is a fourth-generation synthetic fluoroquinolone compound with antibacterial activity against both gram-positive and gram-negative bacteria

• It also shows an inhibitory activity against topoisomerase II

• Moxifloxacin hydrochloride can bind to and inhibit both bacterial enzymes DNA gyrase (topoisomerase II) and topoisomerase IV, resulting in DNA replication and repair inhibition thus induce cell death in sensitive bacterial species

• Moxifloxacin has 100 times higher affinity for bacterial DNA gyrase compared to mammalian DNA gyrase

Applications

• Moxifloxacin hydrochloride presents a higher anti-gram-positive activity compared to other fluoroquinolone such as ciprofloxacin and ofloxacin

• It has immunosuppressive activity that inhibits the proliferation of all classes of lymphocytes, which can induce apoptosis of antigen-presenting T cells

• It is a cytostatic anthracenedione that can intercalate DNA, increasing the occurence of double-strand breaks by stabilizing the cleavable complex of topoisomerase II and DNA

• This compound shows anticancer activity in some animal models presenting leukemia

• Moxifloxacin is being investigated for the treatment of multidrug-resistant tuberculosis strains

TRUSTED_SUSTAINABILITY
Specifications

Specifications

Moxifloxacin Hydrochloride
324.0°C to 325.0°C
5% max.
C21H25ClFN3O4
COC1=C2C(=CC(=C1N3CC4CCCNC4C3)F)C(=O)C(=CN2C5CC5)C(=O)O.Cl
437.896
CHEBI:7008
≥97.5% (HPLC)
186826-86-8
Authentic
1 g
IDIIJJHBXUESQI-DFIJPDEKSA-N
7-[(4aS,7aS)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylic acid;hydrochloride
101526
437.89
Moxifloxacin hydrochloride
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Thermo Scientific Chemicals Moxifloxacin hydrochloride > 1g; Glass bottle

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