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MFN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00 EUR - 410.00 EUR

Specifications

Antigen MFN1
Concentration 0.3 mg/mL
Applications Western Blot, Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16832194
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Proteintech
13798-1-AP-20UL
20 μL
145.00 EUR
20µL
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16822194
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Proteintech
13798-1-AP-150UL
150 μL
410.00 EUR
150µL
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Description

Description

Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development. When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane.
Specifications

Specifications

MFN1
Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
Mouse, Rat, Human
Q811U4, Q8IWA4, Q8R4Z9
192647, 55669, 67414
MFN1 Fusion Protein Ag4762
Primary
-20°C
MFN1
0.3 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Fzo homolog, hfzo1, hfzo2, MFN1, mitofusin 1, Transmembrane GTPase MFN1
MFN1
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
Documents

Documents

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