missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Salts and Inorganics
  5. Inorganic Salts
  6. Metalloid Salts
  7. Lithium bis(trimethylsilyl)amide, 20% (ca 1.06M) soln. in THF/ethylbenzene, packaged in resealable septum cap bottle, Thermo Scientific Chemicals

Lithium bis(trimethylsilyl)amide, 20% (ca 1.06M) soln. in THF/ethylbenzene, packaged in resealable septum cap bottle, Thermo Scientific Chemicals

94.57 EUR - 271.00 EUR

Chemical Identifiers

CAS 4039-32-1
Molecular Formula C6H18LiNSi2
Molecular Weight (g/mol) 167.327
MDL Number MFCD00008261
InChI Key YNESATAKKCNGOF-UHFFFAOYSA-N
Synonym lithium bis trimethylsilyl amide, lithium hexamethyldisilazide, lihmds, lhmds, hexamethyldisilazane lithium salt, unii-rc4n1i108m, lithiumbis trimethylsilyl amide, lithium bis trimethylsilyl azanide, lithium hexamethyldisilazane, lithium bis-trimethylsilyl amide
PubChem CID 2733832
IUPAC Name lithium;bis(trimethylsilyl)azanide
SMILES [Li+].C[Si](C)(C)[N-][Si](C)(C)C
View More Specs

Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
11388106
View Documents
missing translation for 'viewProductCertificates'
Thermo Scientific Alfa Aesar
L15012.AE 		100 mL
94.57 EUR
100mL
Please to purchase this item. Need a web account? Register with us today!
11398106
View Documents
missing translation for 'viewProductCertificates'
Thermo Scientific Alfa Aesar
L15012.AP 		500 mL This item is currently unavailable or has been discontinued.
View the product page for possible alternatives.
 		N/A
Description

Description

Lithium bis(trimethylsilyl)amide is used in generating enolates for preparing lactone precursors, pyranones, and cyclohexanes. It is used to catalyze the addition of phosphine P-H bonds to carbodiimides leading to phosphaguanidines and in a novel three-step synthesis of disubstituted 1,2,5-thiadiazoles. It is also used in the lithiation of ethyl acetate and in the stereospecific Wadsworth-Emmons synthesis of fluoroalkenes from (E)- and (Z)-fluorovinyl sulfones.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Lithium bis(trimethylsilyl)amide is used in generating enolates for preparing lactone precursors, pyranones, and cyclohexanes. It is used to catalyze the addition of phosphine P-H bonds to carbodiimides leading to phosphaguanidines and in a novel three-step synthesis of disubstituted 1,2,5-thiadiazoles. It is also used in the lithiation of ethyl acetate and in the stereospecific Wadsworth-Emmons synthesis of fluoroalkenes from (E)- and (Z)-fluorovinyl sulfones.

Solubility
Reacts with water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Store under inert gas. Incompatible with oxidizing agents.
Specifications

Chemical Identifiers

4039-32-1
167.327
YNESATAKKCNGOF-UHFFFAOYSA-N
2733832
[Li+].C[Si](C)(C)[N-][Si](C)(C)C
C6H18LiNSi2
MFCD00008261
lithium bis trimethylsilyl amide, lithium hexamethyldisilazide, lihmds, lhmds, hexamethyldisilazane lithium salt, unii-rc4n1i108m, lithiumbis trimethylsilyl amide, lithium bis trimethylsilyl azanide, lithium hexamethyldisilazane, lithium bis-trimethylsilyl amide
lithium;bis(trimethylsilyl)azanide

Specifications

4039-32-1
[(CH3)3Si]2NLi
UN2924
−17°C (1°F)
Reacts with water.
[Li+].C[Si](C)(C)[N-][Si](C)(C)C
167.327
167.33
Air and moisture sensitive
Lithium bis(trimethylsilyl)amide, packaged in resealable septum cap bottle
C6H18LiNSi2
MFCD00008261
8136861
lithium bis trimethylsilyl amide, lithium hexamethyldisilazide, lihmds, lhmds, hexamethyldisilazane lithium salt, unii-rc4n1i108m, lithiumbis trimethylsilyl amide, lithium bis trimethylsilyl azanide, lithium hexamethyldisilazane, lithium bis-trimethylsilyl amide
YNESATAKKCNGOF-UHFFFAOYSA-N
lithium;bis(trimethylsilyl)azanide
2733832
20% (≈1.06M) soln. in THF/ethylbenzene
0.891
Videos
Safety and Handling

Safety and Handling

GHS H Statement
H225-H314-H351-H335
Highly flammable liquid and vapor.
Causes severe skin burns and eye damage.
Suspected of causing cancer.
May cause respiratory irritation.

P201-P202-P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P281-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P501c

H225-H302-H304-H314-H335-H336-H351

missing translation for 'dotInformation' : Transport Hazard Class: 3; Packing Group: II; Proper Shipping Name: FLAMMABLE LIQUIDS, CORROSIVE, N.O.S.

missing translation for 'einecsNumber' : 223-725-6

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures; Store under Nitrogen

Product Identifier
  • Lithium bis(trimethylsilyl)amide, 20% solution in THF/ethylbenzene

Signal Word
  • Danger

Hazard Category
  • Aspiration toxicity Category 1
  • Carcinogenicity Category 2
  • Serious eye damage/eye irritation Category 1
  • Skin corrosion/irritation Category 1 B
  • Specific target organ toxicity Category 3

Hazard Statement
  • H304-May be fatal if swallowed and enters airways.
  • H314-Causes severe skin burns and eye damage.
  • H318-Causes serious eye damage.
  • H335-May cause respiratory irritation.
  • H336-May cause drowsiness or dizziness.
  • H351-Suspected of causing cancer.
  • EUH014-Reacts violently with water.
  • EUH019-May form explosive peroxides.

Precautionary Statement
  • P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310-Immediately call a POISON CENTER/doctor/.

Supplemental information
  • MIXTURE LIST-Contains : Tetrahydrofuran, eth

SDS
Documents

Documents

Product Certifications

RUO – Research Use Only