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EIF3E Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
145.00 EUR - 410.00 EUR
Specifications
Antigen | EIF3E |
---|---|
Concentration | 0.25 mg/mL |
Applications | Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16827593
|
Proteintech
10899-1-AP-20UL |
20 μL |
145.00 EUR
20µL |
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16817593
|
Proteintech
10899-1-AP-150UL |
150 μL |
410.00 EUR
150µL |
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Description
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.Specifications
EIF3E | |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
Unconjugated | |
Rabbit | |
Rat, Mouse, Human | |
P60228, P60229, Q641X8 | |
103692906, 16341, 3646 | |
EIF3E Fusion Protein Ag1132 | |
Primary | |
-20°C | |
EIF3E |
0.25 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
eIF 3 p48, eIF3 p46, EIF3 P48, EIF3E, EIF3S6, INT6 | |
EIF3E | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |
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