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Doxorubicin Hydrochloride, Fisher BioReagents

36.94 EUR - 1340.00 EUR

Chemical Identifiers

CAS 25316-40-9
Molecular Formula C27H30ClNO11
Molecular Weight (g/mol) 579.98
MDL Number MFCD00077757,MFCD00077757,MFCD00941448
InChI Key MWWSFMDVAYGXBV-FGBJBKNOSA-N
Synonym doxorubicin hydrochloride, adriamycin, doxorubicin hcl, adriacin, adriblastina, rubex, adriamycin hydrochloride, adriblastin, adriamycin pfs
PubChem CID 129626538
IUPAC Name (7R,9R)-7-[(2S,4R,5R,6R)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride
SMILES [H+].[Cl-].COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3OC3CC(N)C(O)C(C)O3)C(=O)CO)C(O)=C1C2=O
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Description

Description

Doxorubicin Hydrochloride

Doxorubicin HCL is a chemotherapeutic agent. Antitumor, immunosuppressive, and antibiotic agent. It blocks RNA polymerase and reverse transcriptase. Also inhibits nucleic acid synthesis.
Specifications

Chemical Identifiers

25316-40-9
579.98
MWWSFMDVAYGXBV-FGBJBKNOSA-N
129626538
[H+].[Cl-].COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3OC3CC(N)C(O)C(C)O3)C(=O)CO)C(O)=C1C2=O
C27H30ClNO11
MFCD00077757,MFCD00077757,MFCD00941448
doxorubicin hydrochloride, adriamycin, doxorubicin hcl, adriacin, adriblastina, rubex, adriamycin hydrochloride, adriblastin, adriamycin pfs
(7R,9R)-7-[(2S,4R,5R,6R)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride

Specifications

25316-40-9
216°C
(by HPLC): ≥95%
MFCD00077757,MFCD00077757,MFCD00941448
doxorubicin hydrochloride, adriamycin, doxorubicin hcl, adriacin, adriblastina, rubex, adriamycin hydrochloride, adriblastin, adriamycin pfs
MWWSFMDVAYGXBV-FGBJBKNOSA-N
(7R,9R)-7-[(2S,4R,5R,6R)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride
129626538
Powder or Solid
216°C
Orange
C27H30ClNO11
15, 3487
Soluble in water
[H+].[Cl-].COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3OC3CC(N)C(O)C(C)O3)C(=O)CO)C(O)=C1C2=O
579.98
580
Doxorubicin Hydrochloride
Videos
Safety and Handling

Safety and Handling

WARNING!

Emergency Overview
May cause cancer. Risk of serious damage to eyes. Irritating to respiratory system and skin. May cause heritable genetic damage. Possible risk of impaired fertility. Possible risk of harm to the unborn child. Use personal protective equipment. Use only under a chemical fume hood. Wash off immediately with plenty of water for at least 15 minutes. Obtain medical attention. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required. Immediate medical attention is required. Move to fresh air.

NFPA

Health:2
Flammability:1
Instability:0

Recommended Storage : 2° to 8°C

Product Identifier
  • Doxorubicin hydrochloride

Signal Word
  • Danger

Hazard Category
  • Acute toxicity Category 4
  • Carcinogenicity Category 1B
  • Serious eye damage/eye irritation Category 1
  • Germ cell mutagenicity Category 1B
  • Reproductive toxicity Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3

Hazard Statement
  • H318-Causes serious eye damage.
  • H340-May cause genetic defects.
  • H350-May cause cancer.
  • H315-Causes skin irritation.
  • H361fd-Suspected of damaging fertility. Suspected of damaging the unborn child.
  • H335-May cause respiratory irritation.
  • H302-Harmful if swallowed.

Precautionary Statement
  • P201-Obtain special instructions before use.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310-Immediately call a POISON CENTER/doctor/.

SDS
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