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Chromomycin A3, 97%

CAS: 7059-24-7 | C57H82O26 | 1183.257 g/mol

Brand: Thermo Scientific Alfa Aesar J62927.MA

Quantity	10 mg

Product Code. 15415229

412.00 EUR / 10mg

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Description

Chromomycin A3, is used as a G-C specific DNA ligand which inhibits transcription and acts as a DNA binding dye. Chromomycin A3 antagonizes enhanced DNA binding of the transcription factors Sp1 and Sp3 to their cognate G-C box, induced by oxidative stress or DNA damage. Furthermore, by inhibiting transcription, Chromomycin A3 and its structural analogs can inhibit protein biosynthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Chromomycin A3, is used as a G-C specific DNA ligand which inhibits transcription and acts as a DNA binding dye. Chromomycin A3 antagonizes enhanced DNA binding of the transcription factors Sp1 and Sp3 to their cognate ″G-C&Pr

Specifications

Type	Chromomycin A3
CAS	7059-24-7
Color	Yellow
Molecular Formula	C57H82O26
UN Number	UN3462
Solubility Information	Soluble in ethanol,DMSO,and ethyl acetate (10mg/ml).
SMILES	CC1C(C(CC(O1)OC2C(CC3=C(C2=O)C(=C4C(=C3)C=C(C(=C4O)C)OC5CC(C(C(O5)C)OC(=O)C)OC6CC(C(C(O6)C)OC)O)O)C(C(=O)C(C(C)O)O)OC)OC7CC(C(C(O7)C)O)OC8CC(C(C(O8)C)OC(=O)C)(C)O)O
Molecular Weight (g/mol)	1183.257
Formula Weight	1183.3
Chemical Name or Material	Chromomycin A3

Physical Form	Powder
Melting Point	185°C (decomposition)
Quantity	10 mg
MDL Number	MFCD00043151
Merck Index	14,2238
InChI Key	ZYVSOIYQKUDENJ-YVQLHGKOSA-N
IUPAC Name	[(2R,3R,4R,6S)-6-[[(6S,7S)-6-[(2S,4R,5R,6R)-4-[(4R,5S,6R)-4-[(2S,4S,5R,6R)-5-acetyloxy-4-hydroxy-4,6-dimethyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]oxy-7-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-4,10-dihydroxy-3-
PubChem CID	23928042
Percent Purity	97%

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Chromomycin A3, 97%

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