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CDC42 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10155-1-AP-150UL

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Product Code. 16816353

  • 410.00 EUR / 150µL

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Description

Description

This protein is a small GTPase of the Rho subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis, and cell progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42 1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrick syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in at least two transcript variants.
Specifications

Specifications

CDC42
Polyclonal
Unconjugated
CDC42
CDC42, CDC42Hs, G25K, G25K GTP binding protein
Rabbit
Antigen Affinity Chromatography
RUO
12540, 64465, 998
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.35 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P60766, P60953, Q8CFN2
Cdc42
CDC42 Fusion Protein Ag0207
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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