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BD Pharmingen™ IHC Zinc Fixative
An alternative to formalin fixation of tissue for paraffin embedded sections
161.00 EUR - 353.00 EUR
Specifications
| Color | Clear |
|---|---|
| Content And Storage | Room temperature |
| Product Type | Fixative |
| For Use With (Application) | Immunohistochemical staining |
| Form | Liquid |
| Product Code | Brand | Dilution | Quantity | Price | Quantity & Availability | ||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Dilution | Quantity | Price | Quantity & Availability | ||||
|
10400275
|
BD
550523 |
1 X | 1000mL |
161.00 EUR
Each |
Estimated Shipment: 29-11-2024
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|
15886838
|
BD
552658 |
10 X | 500mL |
353.00 EUR
Each |
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Description
Ten percent neutral buffered formalin fixes tissue by cross-linking proteins, potentially causing a conformational change or “masking” of the antigenic epitope and leading to reduced or absent antibody reactivity. Different antigen retrieval techniques are used to unmask the epitope; however, many times it is not possible to retrieve the epitope and get optimal immunohistochemical staining. In these situations the use of IHC Zinc fixative, which is a milder fixative than formalin, is recommended.
- Zinc-fixed paraffin embedded sections show very good immunostaining with many leukocytes markers and depict tissue morphology comparable to formalin-fixation
- Use of antigen retrieval techniques on the zinc-fixed paraffin sections may further enhance the antibody reactivity in some cases
There are a few antigens that are not preserved by zinc-fixation. In these situations use of fresh frozen tissue for immunohistochemical staining is the only alternative.
Specifications
| Clear | |
| Fixative | |
| Liquid |
| Room temperature | |
| Immunohistochemical staining |