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ARMETL1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 25035-1-AP-150UL

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Product Code. 16853565

  • 410.00 EUR / 150µL

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Description

Description

The conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor. Somewhat surprisingly, CDCF is expressed at higher levels in tissues such as heart, skeletal muscle and testes than in brain. Similar to the glial cell line-derived neurotrophic factor (GDNF), CDNF can prevent the 6-hydroxylamine (6 OHDA) induced degeneration of dopaminergic neurons in a rat model of Parkinsons disease. Furthermore, CDNF was able to restore the dopaminergic function and prevent the degeneration of dopaminergic neurons in the substantia nigra, suggesting that CDNF might be suitable for the treatment of Parkinsons disease. At least two isoforms of CDNF are known to exist.
Specifications

Specifications

ARMETL1
Polyclonal
Unconjugated
CDNF
ARMET like protein 1, ARMETL1, cdnf
Rabbit
Antigen Affinity Chromatography
RUO
227526, 441549
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.38 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q49AH0, Q8CC36
CDNF
ARMETL1 Fusion Protein Ag18972
150 μL
Primary
Human, Mouse
Antibody
IgG
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