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ANKMY2 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA550324
This item is not returnable.
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Description
The antibody detects endogenous levels of total ANKMY2 protein.
ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicate that ANKMY2 may role a role in the pathogenesis of natural killer (NK)-cell malignancies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, diverts differentiation to an alternative fate and promotes pre-leukaemic states.
Specifications
| ANKMY2 | |
| Polyclonal | |
| Unconjugated | |
| Ankmy2 | |
| AI035571; ANKMY2; ankyrin repeat and MYND domain containing 2; ankyrin repeat and MYND domain-containing protein 2; EGK_13887; Gna14; guanine nucleotide binding protein, alpha 14; LOW QUALITY PROTEIN: ankyrin repeat and MYND domain-containing protein 2; ZMYND20 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 57037 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 1 mg/mL | |
| PBS with 40% glycerol and 0.05% sodium azide; pH 7.4 | |
| Q8IV38 | |
| Ankmy2 | |
| Fusion protein corresponding to residues near the N terminal of human ankyrin repeat and MYND domain containing 2 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |