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Thermo Scientific Chemicals 5-Fluorouracil, 99%
5-Fluorouracil, CAS # 51-21-8, is an analogue base composed of uracil with a position 5 hydrogen fluorine substitution.
31.66 EUR - 949.00 EUR
Chemical Identifiers
| CAS | 51-21-8 |
|---|---|
| Molecular Formula | C4H3FN2O2 |
| Molecular Weight (g/mol) | 130.08 |
| MDL Number | MFCD00006018 |
| InChI Key | GHASVSINZRGABV-UHFFFAOYSA-N |
| Synonym | 5-fluorouracil, fluorouracil, 5-fu, fluoroplex, adrucil, efudex, carac, fluracil, fluoroblastin, kecimeton |
| PubChem CID | 3385 |
| ChEBI | CHEBI:46345 |
| IUPAC Name | 5-fluoro-1H-pyrimidine-2,4-dione |
| SMILES | FC1=CNC(=O)NC1=O |
| Product Code | Brand | Quantity | Packaging | Price | Quantity & Availability | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Packaging | Price | Quantity & Availability | ||||||
|
10348170
|
Thermo Scientific Chemicals
228440010 |
1 g | Glass bottle |
31.66 EUR
1g |
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|
10697552
|
Thermo Scientific Chemicals
228440050 |
5 g | Glass bottle |
96.38 EUR
5g |
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|
11906531
|
Thermo Scientific Chemicals
228440250 |
25 g | Glass bottle |
312.56 EUR
25g |
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|
15159263
|
Thermo Scientific Chemicals
228441000 |
100 g | Glass bottle | N/A | N/A | N/A | |||||
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• 5-Fluorouracil is an antimetabolite and antineoplastic that prevents DNA synthesis by blocking conversion of deoxyuridylic acid
• 5-Fluorouracil can replace uracil in RNA and prevent protein synthesis and cell growth
Applications
• 5-Fluorouracil can be used for laboratory research on tumor growth and immunosuppression
• 5-Fluorouracil may also be appropriate for laboratory studies of neurotoxicity, cell lysis, and DNA damage
Chemical Identifiers
| 51-21-8 | |
| 130.08 | |
| GHASVSINZRGABV-UHFFFAOYSA-N | |
| 3385 | |
| 5-fluoro-1H-pyrimidine-2,4-dione |
| C4H3FN2O2 | |
| MFCD00006018 | |
| 5-fluorouracil, fluorouracil, 5-fu, fluoroplex, adrucil, efudex, carac, fluracil, fluoroblastin, kecimeton | |
| CHEBI:46345 | |
| FC1=CNC(=O)NC1=O |
Specifications
| 51-21-8 | |
| White | |
| 0.5% (80°C, 4 hrs) (in vacuum) max. | |
| 99% | |
| MFCD00006018 | |
| 15,4213 | |
| Solubility in water: 12.2g/L (20°C). Other solubilities: 2.9g/L (20°C) in ethanol,readily soluble in aqueous alkali solutions,soluble in dmso | |
| FC1=CNC(=O)NC1=O | |
| 130.08 | |
| CHEBI:46345 | |
| 99% | |
| 5-Fluorouracil |
| 278.0°C to 282.0°C | |
| 190.0°C to 200.0°C (0.1 mmHg) | |
| Authentic | |
| C4H3FN2O2 | |
| 24,IV,1229 | |
| 5-fluorouracil, fluorouracil, 5-fu, fluoroplex, adrucil, efudex, carac, fluracil, fluoroblastin, kecimeton | |
| GHASVSINZRGABV-UHFFFAOYSA-N | |
| 5-fluoro-1H-pyrimidine-2,4-dione | |
| 3385 | |
| 130.08 | |
| Crystalline Powder |
Safety and Handling
GHS H Statement
Suspected of causing genetic defects.
Suspected of damaging the unborn child.
Toxic if swallowed.
Harmful in contact with skin.
Harmful if inhaled.
Causes serious eye irritation.
Causes skin irri
GHS P Statement
Wear protective gloves/protective clothing/eye protection/face protection.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF INHALED: Remove victim to fresh air and keep at rest in a position comforta
GHS Signal Word: Danger
missing translation for 'einecsNumber' : 200-085-6
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
- 5-Fluorouracil
Signal Word
- Danger
Hazard Category
- Acute toxicity Category 3
- Acute toxicity Category 4
- Serious eye damage/eye irritation Category 2
- Germ cell mutagenicity Category 2
- Reproductive toxicity Category 2
- Skin corrosion/irritation Category 2
- Specific target organ toxicity Category 3
Hazard Statement
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H341-Suspected of causing genetic defects.
- H361d-Suspected of damaging the unborn child.
- H335-May cause respiratory irritation.
- H312-Harmful in contact with skin.
- H332-Harmful if inhaled.
- H301-Toxic if swallowed.
Precautionary Statement
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
- P302+P352-IF ON SKIN: Wash with plenty of water/.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P312-Call a POISON CENTER/doctor/if you feel unwell.
- P337+P313-If eye irritation persists: Get medical advice/attention.
RUO – Research Use Only
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Product Title
Thermo Scientific Chemicals 5-Fluorouracil, 99%