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Thermo Scientific Chemicals Trimethoprim, 98%

Trimethoprim, CAS # 738-70-5, is a trimethoxybenzyl-pyrimidine used as an antimicrobial.

81.70 EUR - 913.00 EUR

Chemical Identifiers

CAS 738-70-5
Molecular Formula C14H18N4O3
Molecular Weight (g/mol) 290.32
InChI Key IEDVJHCEMCRBQM-UHFFFAOYSA-N
Synonym trimethoprim, proloprim, trimpex, bactramin, monotrim, monotrimin, trimetoprim, trimopan, monoprim, syraprim
PubChem CID 5578
ChEBI CHEBI:45924
IUPAC Name 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
SMILES COC1=CC(=CC(=C1OC)OC)CC2=CN=C(N=C2N)N
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Thermo Scientific Chemicals
455120050
5 g
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Thermo Scientific Chemicals
455120250
25 g
308.00 EUR
25g
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Thermo Scientific Chemicals
455121000
100 g
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Description

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Trimethoprim is a synthetic pyrimidine analog that binds dihydrofolate-reductase and inhibits the synthesis of folic acid; when paired with sulfamethoxazole, its activity is enhanced • Trimethoprim has antibacterial and antiprotozoal properties

Applications

• Trimethoprim inhibits the conversion of para-aminobenzoic acid (PABA) to folic acid near the end of the synthesis pathway and can be used to study related effects

• Trimethoprim has been radiolabeled and used to trace routes of infection, and it also has been used experimentally as a fluorescent labeler to quantify dihydrofolate-reductase expression

Specifications

Chemical Identifiers

738-70-5
290.32
trimethoprim, proloprim, trimpex, bactramin, monotrim, monotrimin, trimetoprim, trimopan, monoprim, syraprim
CHEBI:45924
COC1=CC(=CC(=C1OC)OC)CC2=CN=C(N=C2N)N
C14H18N4O3
IEDVJHCEMCRBQM-UHFFFAOYSA-N
5578
5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine

Specifications

738-70-5
0.5% max. (105°C, 4 h)
97.5% min. (HPLC)
trimethoprim, proloprim, trimpex, bactramin, monotrim, monotrimin, trimetoprim, trimopan, monoprim, syraprim
IEDVJHCEMCRBQM-UHFFFAOYSA-N
5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
5578
290.32
Trimethoprim
234.0°C to 236.0°C
Authentic
C14H18N4O3
Solubility in water: insoluble.
COC1=CC(=CC(=C1OC)OC)CC2=CN=C(N=C2N)N
290.32
CHEBI:45924
98%
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Safety and Handling

Safety and Handling

GHS H Statement
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

GHS P Statement
IF ON SKIN: Wash with plenty of soap and water.
If eye irritation persists: Get medical advice/attention.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Call a POISON CENTER

GHS Signal Word: Warning

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SDS
Documents

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Product Certifications

RUO – Research Use Only