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TMPRSS2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
140.00 EUR - 399.00 EUR
Specifications
Antigen | TMPRSS2 |
---|---|
Concentration | 0.31 mg/mL |
Applications | Immunohistochemistry (Paraffin), Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16803084
|
Proteintech
14437-1-AP-20UL |
20 μL |
140.00 EUR
20µL |
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16893074
|
Proteintech
14437-1-AP-150UL |
150 μL |
399.00 EUR
150µL |
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Description
Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors. The TMPRSS2 gene encodes a 492 amino acid multimeric serine protease, which is mainly expressed in the mouse prostate and kidney, and is also expressed in the human small intestine, prostate, colon, stomach and salivary gland. TMPRSS2 contains several domains, including a serine protease domain of the S1 family, a scavenger receptor cysteine-rich domain of group A, an LDL receptor class A domain and a transmembrane domain. TMPRSS2 is expressed as a full length form and a cleaved protease domain and its expression is increased by androgenic hormones. TMPRSS2 is also expressed in prostate carcinoma, suggesting that it may play a role in prostate carcinogenesis.Specifications
TMPRSS2 | |
Immunohistochemistry (Paraffin), Western Blot | |
Unconjugated | |
Rabbit | |
Mouse, Rat, Human | |
O15393, Q9JIQ8 | |
156435, 50528, 7113 | |
TMPRSS2 Fusion Protein Ag5824 | |
Primary | |
-20°C | |
TMPRSS2 |
0.31 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
PP9284, PRSS10, Serine protease 10, TMPRSS2 | |
Tmprss2 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |