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Guanidine Hydrochloride, Ultra Pure grade, MP Biomedicals

87.13 EUR - 523.64 EUR

Chemical Identifiers

CAS 50-01-1
Molecular Formula CH6ClN3
Molecular Weight (g/mol) 95.53
MDL Number MFCD00013026
InChI Key PJJJBBJSCAKJQF-UHFFFAOYSA-N
Synonym guanidine hydrochloride, guanidinium chloride, guanidine, monohydrochloride, aminoformamidine hydrochloride, aminomethanamidine hydrochloride, guanidine monohydrochloride, guanidine hcl, guanidine chloride, iminourea hydrochloride, carbamidine hydrochloride
PubChem CID 5742
ChEBI CHEBI:32735
IUPAC Name guanidine;hydrochloride
SMILES C(=N)(N)N.Cl
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Product Code Brand Quantity Price Quantity & Availability  
11441682
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MP Biomedicals
04820512
100 g
87.13 EUR
100g
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11461682
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MP Biomedicals
04820540
1 kg
523.64 EUR
1kg
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Description

Description

  • Guanidine Hydrochloride is a strong chaotropic agent useful for the denaturation and subsequent refolding of proteins
  • This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies
  • This can be used as the first step in refolding proteins or enzymes into their active form
  • Urea and dithiothreitol (DTT) may also be necessary
  • Guanidine HCl is used in the isolation of RNA to dissociate the nucleoprotein into its nucleic acid and protein moieties
  • It is an inhibitor of RNase
  • Highly concentrated (6 - 8 M) Guanidine HCl solutions are used to denature native globular proteins
  • It apparently disrupts hydrogen bonds which hold the protein in its unique structure; however, there also is evidence suggesting that guanidine hydrocholoride may disrupt hydrophobic interactions by promoting the solubility of hydrophobic residues in aqueous solutions

Specifications

Chemical Identifiers

50-01-1
95.53
PJJJBBJSCAKJQF-UHFFFAOYSA-N
5742
guanidine;hydrochloride
CH6ClN3
MFCD00013026
guanidine hydrochloride, guanidinium chloride, guanidine, monohydrochloride, aminoformamidine hydrochloride, aminomethanamidine hydrochloride, guanidine monohydrochloride, guanidine hcl, guanidine chloride, iminourea hydrochloride, carbamidine hydrochloride
CHEBI:32735
C(=N)(N)N.Cl

Specifications

50-01-1
White
CH5N3·HCl
guanidine hydrochloride, guanidinium chloride, guanidine, monohydrochloride, aminoformamidine hydrochloride, aminomethanamidine hydrochloride, guanidine monohydrochloride, guanidine hcl, guanidine chloride, iminourea hydrochloride, carbamidine hydrochloride
PJJJBBJSCAKJQF-UHFFFAOYSA-N
guanidine;hydrochloride
5742
95.53
Ultra Pure
GUANIDINE HYDROCHLORIDE
180°C to 190°C
CH6ClN3
MFCD00013026
Soluble in water (6 M - clear, colorless solution).
C(=N)(N)N.Cl
95.53
CHEBI:32735
≥99%
Crystalline Powder
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Safety and Handling

Safety and Handling

Recommended Storage : Store at Room Temperature (15-30°C). Store Desiccated.

Product Identifier
  • Guanidine Hydrochloride, ultra pure

Signal Word
  • Warning

Hazard Category
  • Acute toxicity Category 4
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2

Hazard Statement
  • H302-Harmful if swallowed.
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.

Precautionary Statement
  • P260-Do not breathe dust/fume/gas/mist/vapours/spray.
  • P264-Wash thoroughly after handling.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P321-Specific treatment (see on this label).
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information
  • MIXTURE LIST-Contains : guanadine hydrochloride

SDS
Documents

Documents

Product Certifications