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Dextran Sulfate Sodium Salt, Colitis Grade (36,000 to 50,000), MP Biomedicals™

Induces severe colitis (inflammatory bowel disease) in laboratory animals

196.00 EUR - 4040.00 EUR

Specifications

Color White
pH 5 to 7.11 (1% aqueous solution)
CAS 9011-18-1
Physical Form Powder
Boiling Point 310°C
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0216011010
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0216011050
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0216011080
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Description

Description

Induces severe colitis (inflammatory bowel disease) in laboratory animals

Dextran sulfate sodium salt, or DSS, is a synthetic sulfated branched polysaccharide derivative of dextran that has multiple uses in biomedical and clinical research. One important property of DSS is to trigger colitis in mice and rats when administered in drinking water. DSS binds to medium-chain-length fatty acids in the colon and induces intestinal inflammation. Colitis-grade DSS (MW = 36,000 to 50,000) from MP Bio is one of the most widely used products based on peer reviewed scientific publications.

  • Induces severe colitis (inflammatory bowel disease)
  • Highest sulfur content – 19%
  • Highest chirality - +104° of specific rotation
  • Lowest pH – 6.2 at 1% solution
Specifications

Specifications

White
9011-18-1
310°C
MFCD00081551
Colitis Grade
<10%
5 to 7.11 (1% aqueous solution)
Powder
92°C
Soluble in water
Used for inducing ulcerative colitis in animals and extensively to study colon cancer developing in relation to colonic inflammation
Plastic Container
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Safety and Handling

Safety and Handling

missing translation for 'storageNote' : Store at Room Temperature (15°C to 30°C)

SDS
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Product Certifications

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use.