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  6. Thermo Scientific Chemicals Colchicine, 97%

Thermo Scientific Chemicals Colchicine, 97%

Product Code. 10174953
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Quantity:
500 mg
1 g
5 g
25 g
Packaging:
Glass bottle

Description

Colchicine, 7alphah-colchicine, CAS # 64-86-8, is a laboratory grade formulation of the anti-inflammatory plant alkaloid drug.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

  • Colchicine (7alphah-colchicine) is an alkaloid found in Colchicum autumnale that has been shown to have anti-gout and anti-inflammatory properties
  • Colchicine binds tubulin and prevents the migration of immune cells, reducing inflammation

Applications

  • Colchicine is an anti-mitotic; may be used in the study of cell proliferation and migration
  • Intended for in vivo and in vitro research applications
  • For research use only, not intended to treat disease
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 64-86-8
Molecular Formula C22H25NO6
Molecular Weight (g/mol) 399.44
MDL Number MFCD00078484,MFCD00078484
InChI Key IAKHMKGGTNLKSZ-INIZCTEOSA-N
Synonym colchicine, colchicina, colchicin, condylon, colchicinum, colchisol, colsaloid, colcin, colchineos, 7alphah-colchicine
PubChem CID 45038708
IUPAC Name 2,2,2-trideuterio-N-[(7S)-1,2,3-trimethoxy-9-oxo-10-(trideuteriomethoxy)-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
SMILES COC1=C(OC)C(OC)=C2C(CC[C@H](NC(C)=O)C3=CC(=O)C(OC)=CC=C23)=C1

Specifications

Melting Point 150.0°C to 160.0°C
Color Yellow
Infrared Spectrum Authentic
Assay Percent Range 96% min. on anhydrous and solvent-free substance (HPLC)
Packaging Glass bottle
Quantity 5 g
Beilstein 14,IV,946
Merck Index 15,2455
Specific Rotation Condition − 250.00 (20.00°C c=1,alcohol)
Specific Rotation − 250.00
Solubility Information Solubility in water: 45g/l (20°C). Other solubilities: soluble in alcohol and chloroform,practically insoluble in petroleum ether,1g/220mL ether,1g/100mL benzene
Formula Weight 399.44
Percent Purity 97%
Physical Form Powder
Chemical Name or Material Colchicine
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Safety and Handling

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Product Identifier
  • Colchicine
 Signal Word
  • Danger
 Hazard Category
  • Acute toxicity Category 2
  • Germ cell mutagenicity Category 1B
 Hazard Statement
  • H340-May cause genetic defects.
  • H300-Fatal if swallowed.
 Precautionary Statement
  • P201-Obtain special instructions before use.
  • P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
  • P308+P313-IF exposed or concerned: Get medical advice/attention.

RUO – Research Use Only

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