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ARMETL1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 25035-1-AP-20UL
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Description
The conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor. Somewhat surprisingly, CDCF is expressed at higher levels in tissues such as heart, skeletal muscle and testes than in brain. Similar to the glial cell line-derived neurotrophic factor (GDNF), CDNF can prevent the 6-hydroxylamine (6 OHDA) induced degeneration of dopaminergic neurons in a rat model of Parkinsons disease. Furthermore, CDNF was able to restore the dopaminergic function and prevent the degeneration of dopaminergic neurons in the substantia nigra, suggesting that CDNF might be suitable for the treatment of Parkinsons disease. At least two isoforms of CDNF are known to exist.Specifications
| ARMETL1 | |
| Polyclonal | |
| Unconjugated | |
| CDNF | |
| ARMET like protein 1, ARMETL1, cdnf | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 227526, 441549 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.38 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q49AH0, Q8CC36 | |
| CDNF | |
| ARMETL1 Fusion Protein Ag18972 | |
| 20 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |